Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 12/20 | 0.38 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953301 | 0.79 | MAPK1 (0.54) | — | |
| SCHEMBL6664934 | 0.78 | CYP2C19 (0.37) | ITKCYP2C19ALDH1A1TSHR | |
| SCHEMBL5953522 | 0.77 | MAPK3 (0.39) | ITKMAP3K8TSHR | |
| SCHEMBL5953529 | 0.76 | ITK (0.42) | ITK | |
| SCHEMBL5952249 | 0.76 | MAPK1 (0.41) | ITK | |
| SCHEMBL5953002 | 0.76 | MAPK1 (0.41) | ITK | |
| SCHEMBL5952946 | 0.76 | PIP5K1C (0.42) | ITK | |
| SCHEMBL5953090 | 0.76 | MAPK1 (0.41) | ITK | |
| SCHEMBL5953516 | 0.76 | MAPK3 (0.41) | ITKCYP2C19 | |
| SCHEMBL5952126 | 0.76 | BRD4 (0.43) | ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048868-A1 | Benzimidazoles | AVENTISUB LLC | 2004-03-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048868-A1 | Benzimidazoles | CDK9, BMX, CDKN1A | ITK 1317/4885MAP3K8 40/4885CYP2C19 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.