Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727072 | 0.88 | RAD52 (0.49) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6732194 | 0.87 | RXFP1 (0.46) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6610256 | 0.87 | RAD52 (0.48) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6724236 | 0.86 | RAD52 (0.45) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6770420 | 0.83 | PDE4B (0.43) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6605450 | 0.81 | KMT2A (0.46) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6724134 | 0.81 | ALDH1A1 (0.46) | RAD52UHRF1KMT2AALDH1A1POLB | |
| SCHEMBL6769426 | 0.78 | KMT2A (0.39) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL6770778 | 0.76 | KCNH2 (0.53) | ALDH1A1RXFP1TSHR | |
| SCHEMBL7938727 | 0.70 | KMT2A (0.50) | RAD52KMT2AALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683181-B2 | MIXING POLYSTYRENE-TOSYL CHLORIDE RESIN WITH C2-12ALKYNOL; REACTING WITH AMINE TO MAKE CHEMICAL INTERMEDIATE; HERPES VIRUS TREATMENT | PHARMACIA AND UPJOHN COMAPNY | 2004-01-27 | — | — | US | disclosed |
| US-20030153561-A1 | Pyrroloquinolones as antiviral agents | VAILLANCOURT VALERIE A (US) | 2003-08-14 | — | — | US | disclosed |
| EP-1299386-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6525049-B2 | Such as N-(4-chlorobenzyl)-2-(hydroxymethyl)-6-oxo-6H-pyrrolo (3,2,1-ij)quinoline-5-carboxamide for treatment of herpes | PHARMACIA & UPJOHN COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-20020055636-A1 | Pyrroloquinolones as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2002-05-09 | — | — | US | disclosed |
| WO-2002002558-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153561-A1 | Pyrroloquinolones as antiviral agents | ZC3HAV1, ZC3HAV1L, IRF3 | RAD52 754/4885UHRF1 733/4885KMT2A 2367/4885 |
| US-20020055636-A1 | Pyrroloquinolones as antiviral agents | ZC3HAV1, ZC3HAV1L, IRF3 | RAD52 754/4885UHRF1 733/4885KMT2A 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.