⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157505 | 0.78 | — | — | |
| SCHEMBL1159917 | 0.75 | — | — | |
| SCHEMBL9472574 | 0.75 | GAA (0.30) | — | |
| SCHEMBL3952884 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL4342918 | 0.71 | — | — | |
| SCHEMBL948922 | 0.71 | — | — | |
| SCHEMBL20824808 | 0.68 | RAB9A (0.30) | — | |
| SCHEMBL13379597 | 0.67 | — | — | |
| SCHEMBL4620453 | 0.67 | MAP3K14 (0.40) | — | |
| SCHEMBL2224163 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737443-A1 | SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Tanabe Pharma Corporation (JP) | 2026-05-06 | — | — | EP | claimed |
| US-20260062387-A1 | SALT-INDUCIBLE KINASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-03-05 | — | — | US | claimed |
| WO-2024242169-A1 | SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 田辺三菱製薬株式会社 | 2024-11-28 | — | — | WO | claimed |
| CN-117820312-A | Synthesis method of tetrahydroisoquinolone tetracyclic compound | 常州大学 | 2024-04-05 | — | — | CN | claimed |
| US-11878020-B2 | Modulators of Rho-associated protein kinase | REDX PHARMA PLC (GB) | 2024-01-23 | — | — | US | claimed |
| US-20230021916-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LIMITED (GB) | 2023-01-26 | — | — | US | claimed |
| US-11497751-B2 | Modulators of Rho-associated protein kinase | REDX PHARMA PLC (GB) | 2022-11-15 | — | — | US | claimed |
| EP-4026834-A1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | Redx Pharma Plc (GB) | 2022-07-13 | — | — | EP | claimed |
| EP-3743420-B1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA PLC (GB) | 2021-12-15 | — | — | EP | claimed |
| US-20210038606-A1 | Modulators of Rho-associated Protein Kinase | REDX PHARMA LIMITED (GB) | 2021-02-11 | — | — | US | claimed |
| WO-1994013272-A1 | USE OF POTASSIUM CHANNEL ACTIVATORS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF PAIN | SMITHKLINE BEECHAM PLC. (GB) | 1994-06-23 | — | — | WO | claimed |
| EP-0575749-A2 | Use of potassium-channel activators for the manufacture of a medicament for the treatment of gastrointertinal ulcers | E.R. SQUIBB & SONS, INC. (US) | 1993-12-29 | — | — | EP | claimed |
| US-5262419-A | Antiulcer agents | E. R. SQUIBB & SONS, INC. (US) | 1993-11-16 | — | — | US | claimed |
| EP-0528553-A1 | Tetrahydroisoquinoline derivatives, processes for producing the same and fungicides containing the same | TOSOH CORPORATION (JP) | 1993-02-24 | — | — | EP | claimed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | claimed |
| EP-0205292-B1 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1991-11-06 | — | — | EP | claimed |
| EP-0372998-A2 | Use of benzopyran derivatives in the treatment of epilepsy | BEECHAM GROUP PLC (GB) | 1990-06-13 | — | — | EP | claimed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | claimed |
| WO-1987007607-A1 | PYRANO (3,2-c) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1987-12-17 | — | — | WO | claimed |
| EP-0205292-A2 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-12-17 | — | — | EP | claimed |