SCHEMBL67710

SCHEMBL67710

O=C1NCCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 12/20 1.00
PARP1 P09874 10/20 1.00
PARP11 Q9NR21 8/20 1.00
PDPK1 O15530 1/20 1.00
CA12 O43570 1/20 0.63
CA9 Q16790 1/20 0.63
TUBB4A P04350 1/20 0.58
TUBB P07437 1/20 0.58
TUBA3C P0DPH7 1/20 0.58
TUBA1B P68363 1/20 0.58
TUBA4A P68366 1/20 0.58
TUBB4B P68371 1/20 0.58
TUBB3 Q13509 1/20 0.58
TUBB2A Q13885 1/20 0.58
TUBB8 Q3ZCM7 1/20 0.58
TUBA3E Q6PEY2 1/20 0.58
TUBA1A Q71U36 1/20 0.58
TUBA1C Q9BQE3 1/20 0.58
TUBB6 Q9BUF5 1/20 0.58
TUBB2B Q9BVA1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29369705 1.00 PARP10 (1.00) PARP10PARP1PARP11PDPK1CA12
Hydrochloric Acid SCHEMBL29896921 0.98 PARP10 (0.96) PARP10PARP1PARP11PDPK1CA12
Hydrochloric Acid SCHEMBL10647408 0.98 PARP10 (0.96) PARP10PARP1PARP11PDPK1CA12
Piperazine SCHEMBL28321362 0.94 PARP10 (0.89) PARP10PARP1PARP11PDPK1CA12
SCHEMBL1894080 0.88 PARP10 (0.78) PARP10PARP1PARP11PDPK1CA12
SCHEMBL20076060 0.86 PARP10 (0.75) PARP10PARP1PARP11PDPK1CA12
SCHEMBL29752161 0.86 PARP10 (0.75) PARP10PARP1PARP11PDPK1CA12
Trifluoroacetic Acid SCHEMBL28415123 0.85 PARP10 (0.72) PARP10PARP1PARP11PDPK1CA12
SCHEMBL28691391 0.82 PARP1 (0.68) PARP10PARP1PARP11PDPK1CA12
SCHEMBL30114663 0.81 PARP10 (0.67) PARP10PARP1PARP11PDPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3021 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737443-A1 SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Tanabe Pharma Corporation (JP) 2026-05-06 EP claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
US-20260062387-A1 SALT-INDUCIBLE KINASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-03-05 US claimed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US claimed
EP-4653437-A2 NOVEL HETEROCYCLIC COMPOUNDS Innovo Therapeutics Inc. (KR) 2025-11-26 EP claimed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
WO-2025064641-A1 SYNTHETIC COMPOUNDS COMPRISING DIHYDROISOQUINOLINONE MONOMERS SRI INTERNATIONAL (US) 2025-03-27 WO claimed
EP-4514784-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-03-05 EP claimed
EP-4050006-B1 BICYCLIC COMPOUND AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2025-01-01 EP claimed
WO-2024242169-A1 SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 田辺三菱製薬株式会社 2024-11-28 WO claimed
EP-0575749-A2 Use of potassium-channel activators for the manufacture of a medicament for the treatment of gastrointertinal ulcers E.R. SQUIBB & SONS, INC. (US) 1993-12-29 EP claimed
US-5262419-A Antiulcer agents E. R. SQUIBB & SONS, INC. (US) 1993-11-16 US claimed
EP-0528553-A1 Tetrahydroisoquinoline derivatives, processes for producing the same and fungicides containing the same TOSOH CORPORATION (JP) 1993-02-24 EP claimed
EP-0250077-B1 PHARMACOLOGICALLY ACTIVE BENZOPYRANES BEECHAM GROUP PLC (GB) 1992-01-02 EP claimed
EP-0205292-B1 Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1991-11-06 EP claimed
EP-0372998-A2 Use of benzopyran derivatives in the treatment of epilepsy BEECHAM GROUP PLC (GB) 1990-06-13 EP claimed
EP-0250077-A2 Pharmacologically active benzopyranes BEECHAM GROUP PLC (GB) 1987-12-23 EP claimed
WO-1987007607-A1 PYRANO (3,2-c) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP P.L.C. (GB) 1987-12-17 WO claimed
EP-0205292-A2 Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1986-12-17 EP claimed
EP-0096006-A2 3-(Ureidocyclohexylamino)-propane-1,2-diol derivatives, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use CIBA-GEIGY AG (CH) 1983-12-07 EP claimed