Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6771038 | 0.98 | ROCK1 (0.48) | ROCK1F10DYRK1AGSK3BREN | |
| Trifluoroacetic Acid SCHEMBL6770954 | 0.87 | F10 (0.63) | F10F2F7 | |
| Trifluoroacetic Acid SCHEMBL6775615 | 0.84 | F10 (0.60) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6769158 | 0.83 | ROCK1 (0.45) | ROCK1F10DYRK1AGSK3BCHEK2 | |
| Trifluoroacetic Acid SCHEMBL6890249 | 0.83 | F10 (0.49) | ROCK1F10 | |
| Trifluoroacetic Acid SCHEMBL6770182 | 0.81 | NPC1 (0.42) | F10 | |
| Trifluoroacetic Acid SCHEMBL6765882 | 0.81 | F10 (0.56) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL3896028 | 0.81 | F10 (0.68) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6770318 | 0.80 | TRPV1 (0.42) | ROCK1F10 | |
| Trifluoroacetic Acid SCHEMBL6769455 | 0.80 | F10 (0.45) | F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |