Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6771145 | 0.83 | ROCK1 (0.48) | ROCK1GSK3BDYRK1AKCNH2ROCK2 | |
| Trifluoroacetic Acid SCHEMBL6771038 | 0.83 | ROCK1 (0.48) | ROCK1GSK3BDYRK1AKCNH2ROCK2 | |
| Trifluoroacetic Acid SCHEMBL3901004 | 0.74 | F10 (0.55) | MAPTF2F10 | |
| Trifluoroacetic Acid SCHEMBL6770954 | 0.73 | F10 (0.63) | MAPTF2F10 | |
| Trifluoroacetic Acid SCHEMBL6775615 | 0.72 | F10 (0.60) | MAPTOPRD1F2F10 | |
| Trifluoroacetic Acid SCHEMBL6770182 | 0.71 | NPC1 (0.42) | F10 | |
| Trifluoroacetic Acid SCHEMBL6775232 | 0.71 | RAD52 (0.42) | MAPTF10 | |
| SCHEMBL6770185 | 0.70 | TBXAS1 (0.36) | CHEK2CNR2KDM4EF10 | |
| Trifluoroacetic Acid SCHEMBL1869116 | 0.69 | TBK1 (0.45) | ROCK1OPRD1SLC6A4 | |
| SCHEMBL6775981 | 0.69 | KDM4E (0.40) | ROCK1KDM4EF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |