Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | RARG | P13631 | 4/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765905 | 0.93 | TP53 (0.45) | HDAC1HDAC6PTPN1PTGDR2RXRA | |
| SCHEMBL4424612 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL4430921 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6765664 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6771219 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6771216 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6770031 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6765666 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6770027 | 0.85 | RARB (0.45) | HDAC1HDAC6PTPN1PTPN12PTPN22 | |
| SCHEMBL6770058 | 0.83 | HDAC3 (0.48) | HDAC1HDAC6PTPN1PTPN12PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |