Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767029 | 0.93 | EDNRB (0.42) | EDNRBEDNRA | |
| SCHEMBL6771345 | 0.89 | EDNRB (0.43) | EDNRBEDNRA | |
| SCHEMBL6771197 | 0.86 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL6773454 | 0.84 | ADAM17 (0.40) | EDNRBEDNRA | |
| SCHEMBL9089410 | 0.81 | EDNRB (0.44) | EDNRBEDNRA | |
| SCHEMBL6771633 | 0.81 | EDNRA (0.44) | EDNRBEDNRA | |
| SCHEMBL6767826 | 0.81 | EDNRB (0.41) | EDNRBEDNRA | |
| SCHEMBL6769798 | 0.80 | EDNRB (0.38) | EDNRBEDNRA | |
| SCHEMBL6770956 | 0.80 | EDNRB (0.40) | EDNRBEDNRA | |
| SCHEMBL8044523 | 0.79 | EDNRB (0.45) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673824-B1 | HYPOTENSIVE AGENTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-6107320-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 2000-08-22 | — | — | US | disclosed |
| US-5514696-A | Phenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 1996-05-07 | — | — | US | disclosed |