Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.62 |
| ▸ | F2 | P00734 | 3/20 | 0.62 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.35 |
| ▸ | F9 | P00740 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771710 | 0.89 | F10 (0.52) | F10F2KLKB1KLK1C1S | |
| Trifluoroacetic Acid SCHEMBL6765882 | 0.84 | F10 (0.56) | F10F2KLKB1KLK1C1S | |
| Trifluoroacetic Acid SCHEMBL6765933 | 0.82 | F10 (0.68) | F10F2F7 | |
| Trifluoroacetic Acid SCHEMBL6769129 | 0.81 | F10 (0.53) | F10F2KLKB1KLK1C1S | |
| Trifluoroacetic Acid SCHEMBL3905673 | 0.81 | F10 (0.92) | F10F2OPRM1OPRD1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6768943 | 0.81 | F10 (0.50) | F10F2KLKB1KLK1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL6768703 | 0.80 | F10 (0.42) | F10F2KLKB1KLK1C1S | |
| Trifluoroacetic Acid SCHEMBL6769821 | 0.78 | F10 (0.51) | F10F2KLKB1KLK1OPRM1 | |
| SCHEMBL13901249 | 0.77 | F10 (1.00) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL3902136 | 0.72 | F10 (0.74) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |