Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6765933

CC(=N)N1CCC(Oc2ccc(C(=O)NCCOc3cc4c(N)nccc4cc3CC(=O)C(=O)O)cc2)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 12/20 0.68
F2 P00734 3/20 0.68
F7 P08709 1/20 0.39
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 1/20 0.36
ROCK1 Q13464 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6770954 0.88 F10 (0.63) F10F2F7MAPTL3MBTL1
Trifluoroacetic Acid SCHEMBL6775615 0.86 F10 (0.60) F10F2MAPTL3MBTL1KMT2A
Trifluoroacetic Acid SCHEMBL3894473 0.85 F10 (0.93) F10F2
Trifluoroacetic Acid SCHEMBL6771709 0.82 F10 (0.62) F10F2F7
SCHEMBL5099121 0.81 F10 (1.00) F10F2
SCHEMBL14132248 0.80 F10 (0.88) F10F2
Trifluoroacetic Acid SCHEMBL6873840 0.77 F10 (0.76) F10F2
Trifluoroacetic Acid SCHEMBL6771145 0.75 ROCK1 (0.48) F10F2F7ROCK1
Trifluoroacetic Acid SCHEMBL7568684 0.75 F10 (0.80) F10F2
Trifluoroacetic Acid SCHEMBL3910305 0.75 F10 (0.90) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6825181-B1 ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X AJINOMOTO CO., INC. (JP) 2004-11-30 US disclosed
EP-1065200-A1 AMINOISOQUINOLINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2001-01-03 EP disclosed