Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027846 | 0.96 | EPHX1 (0.39) | EPHX1EPHX2KDM4EALDH1A1 | |
| SCHEMBL6778648 | 0.88 | TP53 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL6773214 | 0.86 | EPHX1 (0.44) | EPHX1EPHX2GAAKDM4EALDH1A1 | |
| SCHEMBL6778701 | 0.85 | TLR7 (0.40) | — | |
| SCHEMBL1490991 | 0.85 | EPHX1 (0.39) | EPHX1EPHX2GAA | |
| SCHEMBL6782966 | 0.84 | TLR7 (0.39) | EPHX1 | |
| SCHEMBL6775573 | 0.84 | TLR7 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL14500921 | 0.84 | EPHX2 (0.40) | EPHX1EPHX2GAAKDM4EALDH1A1 | |
| SCHEMBL6782676 | 0.84 | EPHX1 (0.41) | EPHX1EPHX2 | |
| SCHEMBL544499 | 0.83 | TLR7 (0.41) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |