Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778648 | 0.95 | TP53 (0.38) | TLR7KMT2AKDM4EALDH1A1 | |
| SCHEMBL13996157 | 0.91 | MEN1 (0.41) | TLR7TLR8TSHRKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5027827 | 0.90 | MEN1 (0.41) | TLR7TLR8TSHRKMT2AKDM4E | |
| SCHEMBL6094643 | 0.87 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL6778701 | 0.85 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6773171 | 0.85 | TSHR (0.38) | TSHRHTR1ADRD2DRD4KMT2A | |
| SCHEMBL6771906 | 0.84 | EPHX1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL6288244 | 0.84 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6094673 | 0.84 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6768601 | 0.83 | TLR7 (0.45) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |