Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidaprilat SCHEMBL7338400 | 1.00 | ACE (1.00) | ACE | |
| Imidaprilat SCHEMBL683544 | 1.00 | ACE (1.00) | ACE | |
| Imidaprilat SCHEMBL7297440 | 0.99 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL7265368 | 0.99 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL7313750 | 0.99 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL28579102 | 0.99 | ACE (0.98) | ACE | |
| SCHEMBL683529 | 0.91 | ACE (0.87) | ACE | |
| SCHEMBL683274 | 0.91 | ACE (0.87) | ACE | |
| SCHEMBL683904 | 0.91 | ACE (0.83) | ACE | |
| Imidapril SCHEMBL22492310 | 0.90 | ACE (1.00) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250082608-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2025-03-13 | — | — | US | claimed |
| EP-4448096-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | Singapore Health Services Pte. Ltd. (SG) | 2024-10-23 | — | — | EP | claimed |
| WO-2023111196-A1 | TREATMENT AND PREVENTION OF GLOMERULAR DISEASE | SINGAPORE HEALTH SERVICES PTE. LTD. (SG) | 2023-06-22 | — | — | WO | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| CN-1659154-B | Process for the preparation of amine stereoisomers | APSINTERM LLC | 2012-05-30 | — | — | CN | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| WO-2005010028-A1 | ALPHA-AMINO ACID BENZOTHIAZOLYLTHIO ESTER AS INTERMEDIATES FOR MANUFACTURE OF ACE INHIBITORS AND PROCESS FOR PREPARATION THEREOF | LUPIN LIMITED (IN) | 2005-02-03 | — | — | WO | claimed |
| EP-1497272-A2 | METHOD OF PREPARING AMINE STEREOISOMERS | Apsinterm, LLC. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003091207-A2 | METHOD OF PREPARING AMINE STEREOISOMERS | APSINTERM, LLC. (US) | 2003-11-06 | — | — | WO | claimed |
| EP-0274230-B1 | USE OF 2-OXO-IMIDAZOLIDINE DERIVATIVES IN THE PROPHYLAXIS AND TREATMENT OF HEART FAILURE | TANABE SEIYAKU CO., LTD. (JP) | 1992-10-14 | — | — | EP | claimed |
| EP-0272849-B1 | USE OF 2-OXO-IMIDAZOLIDINE DERIVATIVES IN THE TREATMENT OF KIDNEY DISEASES | Tanabe Seiyaku Co., Ltd. (JP) | 1992-10-14 | — | — | EP | claimed |
| US-4888339-A | CARDIOTONIC AGENTS; 2-OXOIMIDAZOLIDINE | TANABE SEIYAKU CO., LTD. (JP) | 1989-12-19 | — | — | US | claimed |
| US-4804672-A | UROGENITIAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-02-14 | — | — | US | claimed |
| EP-0274230-A2 | Use of 2-oxo-imidazolidine derivatives in the prophylaxis and treatment of heart failure | TANABE SEIYAKU CO., LTD. (JP) | 1988-07-13 | — | — | EP | claimed |
| EP-0272849-A2 | Use of 2-oxo-imidazolidine derivatives in the treatment of kidney diseases | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-29 | — | — | EP | claimed |
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | claimed |