Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646865 | 0.91 | TSHR (0.71) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL2428547 | 0.90 | PLA2G2A (0.57) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL16584765 | 0.90 | PLA2G2A (0.59) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL4521739 | 0.87 | TSHR (0.72) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL31307947 | 0.87 | TSHR (0.61) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL8579535 | 0.86 | KDM4E (0.57) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL7941034 | 0.86 | TSHR (0.60) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL30438068 | 0.85 | KMT2A (0.58) | TSHRKDM4EPTPN1PTPN2PTPN6 | |
| SCHEMBL8961442 | 0.85 | PTPN1 (0.65) | TSHRPTPN1PTPN2PTPN6CDC25B | |
| SCHEMBL6653761 | 0.84 | SRD5A2 (0.60) | TSHRKDM4EHSD17B10HNF4ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577645-A1 | ENZYME VARIANTS AND USES THEREOF | Samsara Eco Pty Limited (AU) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024040304-A1 | ENZYME VARIANTS AND USES THEREOF | SAMSARA ECO PTY LIMITED (AU) | 2024-02-29 | — | — | WO | disclosed |
| CN-105764883-B | Thermoplastic polymer composition | 美利肯公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-1592729-A | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES CO (US) | 2005-03-09 | — | — | CN | disclosed |
| US-6693123-B2 | (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA | UNIVERSITY OF PITTSBURGH | 2004-02-17 | — | — | US | disclosed |
| EP-0873123-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2003-04-09 | — | — | EP | disclosed |
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | UNIVERSITY OF PITTSBURGH (US) | 2002-12-19 | — | — | US | disclosed |
| EP-0873123-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0873123-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017070-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-05-15 | — | — | WO | disclosed |
| EP-0380677-A1 | FLUORAN COMPOUNDS AND COLOR-FORMING RECORDING MATERIALS CONTAINING SAME | NIPPON SODA CO., LTD. (JP) | 1990-08-08 | — | — | EP | disclosed |
| EP-0133225-B1 | PEPTIDE DERIVATIVES AND THEIR SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM, PROCESS AND INTERMEDIATES FOR THEIR PRODUCTION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-10-19 | — | — | EP | disclosed |
| EP-0133225-A2 | Peptide derivatives and their salts, pharmaceutical preparations containing them, process and intermediates for their production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | LANCL1, FNTB, DHCR7 | TSHR 2542/4885KDM4E 3061/4885PTPN1 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.