Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2357899 | 0.82 | — | — | |
| SCHEMBL6285881 | 0.76 | — | — | |
| SCHEMBL2418897 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3687072 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27505121 | 0.68 | — | — | |
| SCHEMBL9423507 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL27437629 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL7195183 | 0.63 | — | — | |
| SCHEMBL2426065 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL27524868 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285896-B2 | High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom | BOREALIS AG (AT) | 2019-10-16 | — | — | EP | claimed |
| EP-2285893-B2 | POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF | BOREALIS AG (AT) | 2017-09-06 | — | — | EP | claimed |
| EP-2285896-B1 | High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom | BOREALIS AG (AT) | 2016-09-07 | — | — | EP | claimed |
| EP-2285897-B2 | POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM | BOREALIS AG (AT) | 2015-08-26 | — | — | EP | claimed |
| US-8557924-B2 | Polymer compositions and pressure-resistant pipes made therefrom | BOREALIS AG (AT) | 2013-10-15 | — | — | US | claimed |
| US-8530580-B2 | Polymer compositions having improved homogeneity and odour, a method for making them and pipes made thereof | BOREALIS AG | 2013-09-10 | — | — | US | claimed |
| US-8476370-B2 | High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom | BOREALIS AG (AT) | 2013-07-02 | — | — | US | claimed |
| EP-2285897-B1 | POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM | BOREALIS AG (AT) | 2011-12-07 | — | — | EP | claimed |
| US-20110274860-A2 | High Density Polymer Compositions, A Method for Their Preparation and Pressure-Resistant Pipes made Therefrom | BOREALIS AG (AT) | 2011-11-10 | — | — | US | claimed |
| EP-2285893-B1 | POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF | BOREALIS AG (AT) | 2011-09-21 | — | — | EP | claimed |
| US-20110091674-A1 | Polymer Compositions Having Improved Homogeneity and Odour, A Method For Making Them and Pipes Made Thereof | BOREALIS AG (AT) | 2011-04-21 | — | — | US | claimed |
| EP-2285896-A1 | HIGH DENSITY POLYMER COMPOSITIONS, A METHOD FOR THEIR PREPARATION AND PRESSURE-RESISTANT PIPES MADE THEREFROM | Borealis AG (AT) | 2011-02-23 | — | — | EP | claimed |
| EP-2285897-A1 | POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM | Borealis AG (AT) | 2011-02-23 | — | — | EP | claimed |
| EP-2285893-A1 | POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF | Borealis AG (AT) | 2011-02-23 | — | — | EP | claimed |
| WO-2009147023-A1 | POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM | BOREALIS AG (AT) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147021-A1 | POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF | BOREALIS AG (AT) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147022-A1 | HIGH DENSITY POLYMER COMPOSITIONS, A METHOD FOR THEIR PREPARATION AND PRESSURE-RESISTANT PIPES MADE THEREFROM | BOREALIS AG (AT) | 2009-12-10 | — | — | WO | claimed |
| EP-2130863-A1 | High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom | Borealis AG (AT) | 2009-12-09 | — | — | EP | claimed |
| EP-2130859-A1 | Polymer compositions having improved homogeneity and odour, a method for making them and pipes made thereof | Borealis AG (AT) | 2009-12-09 | — | — | EP | claimed |
| EP-2130862-A1 | Polymer compositions and pressure-resistant pipes made thereof | Borealis AG (AT) | 2009-12-09 | — | — | EP | claimed |