Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107819 | 0.89 | F10 (0.51) | F10DEGS1SMN1; SMN2 | |
| SCHEMBL6108391 | 0.85 | F10 (0.53) | F10DEGS1 | |
| Hydrochloric Acid SCHEMBL6774993 | 0.84 | F10 (0.50) | F10DEGS1SMN1; SMN2 | |
| SCHEMBL6773814 | 0.83 | F10 (0.47) | F10SMN1; SMN2 | |
| SCHEMBL6106722 | 0.82 | F10 (0.49) | F10DEGS1 | |
| SCHEMBL6107471 | 0.82 | F10 (0.47) | F10DEGS1 | |
| SCHEMBL6106693 | 0.82 | F10 (0.51) | F10 | |
| Hydrochloric Acid SCHEMBL6108104 | 0.81 | F10 (0.49) | F10DEGS1 | |
| Hydrochloric Acid SCHEMBL6774726 | 0.81 | MCHR1 (0.53) | F10DEGS1 | |
| SCHEMBL6108534 | 0.80 | F10 (0.51) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689780-B1 | PYRIDINE DERIVATIVES | ELI LILLY AND COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1140905-B1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |