Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107029 | 0.88 | F10 (0.55) | F10SMN1; SMN2ALOX15CHEK1RAB9A | |
| SCHEMBL6773080 | 0.83 | F10 (0.52) | F10SMN1; SMN2 | |
| SCHEMBL6106818 | 0.82 | F10 (0.58) | F10 | |
| SCHEMBL6106785 | 0.79 | F10 (0.52) | F10SMN1; SMN2FLT3CHEK1RAB9A | |
| SCHEMBL6110502 | 0.79 | F10 (0.50) | F10CHEK1 | |
| SCHEMBL6107921 | 0.79 | F10 (0.52) | F10SMN1; SMN2ALOX15CHEK1RAB9A | |
| SCHEMBL7447691 | 0.79 | AKT1 (0.46) | F10SMN1; SMN2ALOX15MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL6769487 | 0.79 | F10 (0.47) | F10SMN1; SMN2MAPTRAB9A | |
| SCHEMBL7360534 | 0.77 | CHEK1 (0.45) | SMN1; SMN2PIM1CHEK1 | |
| SCHEMBL6108227 | 0.77 | CHEK1 (0.50) | F10SMN1; SMN2ALOX15CHEK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689780-B1 | PYRIDINE DERIVATIVES | ELI LILLY AND COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1140905-B1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |