Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766820 | 0.75 | GRIN2D (0.40) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL763349 | 0.72 | GRIA1 (0.52) | KDM4ECA12PARP1CA9CYP1A2 | |
| SCHEMBL22928150 | 0.70 | KIF11 (0.53) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL11385706 | 0.69 | KDM4E (0.43) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL5379137 | 0.68 | DAO (0.46) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL765025 | 0.67 | KDM4E (0.42) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL1016001 | 0.67 | CA12 (0.47) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL22619216 | 0.67 | KDM4E (0.42) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL2483323 | 0.67 | POLB (0.52) | KDM4ECA12PARP1CA9DRD2 | |
| SCHEMBL6367421 | 0.67 | KDM4E (0.42) | KDM4ECA12PARP1CA9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |