SCHEMBL677415

SCHEMBL677415

CC(C)(c1cc(Br)c(OCC(O)COc2c(Br)cc(Br)cc2Br)c(Br)c1)c1cc(Br)c(OCC(O)COc2c(Br)cc(C(C)(C)c3cc(Br)c(OCC(O)COc4c(Br)cc(Br)cc4Br)c(Br)c3)cc2Br)c(Br)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
TSHR P16473 2/20 0.48
MAPT P10636 3/20 0.46
HIF1A Q16665 2/20 0.43
ALOX15 P16050 2/20 0.43
ALOX12 P18054 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
CASP1 P29466 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AR P10275 1/20 0.39
CHEK1 O14757 1/20 0.38
DAPK3 O43293 1/20 0.38
RET P07949 1/20 0.38
PDGFRB P09619 1/20 0.38
PIM1 P11309 1/20 0.38
PDGFRA P16234 1/20 0.38
KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14601519 1.00 ALDH1A1 (0.60) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL14681885 0.95 ALDH1A1 (0.56) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL677393 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL16352073 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL13346359 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL16352074 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL13346360 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL14212727 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL21917342 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15
SCHEMBL677425 0.94 ALDH1A1 (0.55) ALDH1A1TSHRMAPTHIF1AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365817-A1 FLAME RETARDANT FORMULATIONS FOR WOOD COATING BROMINE COMPOUNDS LTD. (IL) 2023-11-16 US disclosed
US-20230323087-A1 Antimony Trioxide Free Flame Retardant Polymer Composition LANXESS CORPORATION (US) 2023-10-12 US disclosed
US-20230128079-A1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2023-04-27 US disclosed
US-9315731-B2 High impact polystyrene flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2016-04-19 US disclosed
US-20140039095-A9 HIGH IMPACT POLYSTYRENE FLAME RETARDED COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2014-02-06 US disclosed
US-8524813-B2 Flame-retarded compositions of styrene-containing polymers BROMINE COMPOUNDS LTD. (IL) 2013-09-03 US disclosed
US-20130102703-A1 HIGH IMPACT POLYSTYRENE FLAME RETARDED COMPOSITIONS BAR-YAAKOV YOAV (IL) 2013-04-25 US disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed
US-7759429-B2 Flame-retardant polyester fibers for artificial hair KANEKA CORPORATION (JP) 2010-07-20 US disclosed
US-7759430-B2 Flame retardant polyester fiber for artificial hair KANEKA CORPORATION (JP) 2010-07-20 US disclosed
US-7754792-B2 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2010-07-13 US disclosed
US-20080085957-A1 Flame-Retardant Polyester Artificial Hair KANEKA CORPORATION (JP) 2008-04-10 US disclosed