Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325045 | 0.87 | MMP3 (0.48) | MMP3MMP1MMP13MMP9LMNA | |
| SCHEMBL6321722 | 0.86 | MMP3 (0.49) | MMP3MMP1MMP13MMP9LMNA | |
| SCHEMBL6330949 | 0.85 | MMP3 (0.51) | MMP3LMNACA12CA1CA2 | |
| SCHEMBL6324386 | 0.83 | MMP3 (0.60) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL6322271 | 0.82 | MMP3 (0.59) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL6400652 | 0.76 | MMP3 (0.47) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL6400321 | 0.76 | MMP3 (0.47) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL6774286 | 0.76 | MMP3 (0.47) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL6324383 | 0.72 | MMP3 (0.50) | MMP3MMP1MMP2MMP13MMP14 | |
| SCHEMBL7341391 | 0.72 | MMP3 (1.00) | MMP3MMP1MMP2MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747027-B1 | SELECTIVELY INHIBITS IN VITRO ACTIVITY OF HUMAN MATRIX METALLOPROTEASE-13 OVER IN VITRO ACTIVITY OF HUMAN MATRIX METALLOPROTEASE-1 | PHARMACIA CORPORATION | 2004-06-08 | — | — | US | disclosed |