Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013714 | 0.94 | ECE1 (0.47) | SIRT2ECE1 | |
| SCHEMBL6774369 | 0.83 | ECE1 (0.59) | ECE1 | |
| SCHEMBL6774373 | 0.83 | ECE1 (0.59) | ECE1 | |
| SCHEMBL6781829 | 0.81 | ECE1 (0.44) | ECE1 | |
| SCHEMBL6773908 | 0.81 | ECE1 (0.42) | SIRT2ECE1 | |
| SCHEMBL6776727 | 0.80 | ECE1 (0.48) | ECE1 | |
| SCHEMBL6774677 | 0.78 | ECE1 (0.48) | ECE1 | |
| SCHEMBL6773549 | 0.78 | NLRP3 (0.46) | ECE1 | |
| SCHEMBL6776402 | 0.77 | ECE1 (0.49) | ECE1 | |
| SCHEMBL6770606 | 0.77 | ECE1 (0.49) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716852-B2 | FOR THERAPY OF ARTERIAL HYPERTENSION AND CARDIOVASCULAR DISEASES | LES LABORATORIES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | LES LABORATOIRES SERVIER (FR) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | MME, ACE, ECE1 | SIRT2 3453/4885ECE1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.