SCHEMBL677498

SCHEMBL677498

Cc1cc(Oc2c(C)cc(C(C)(C)c3cc(C)c(Oc4cc(C)c(O)c(C)c4)c(C)c3)cc2C)cc(C)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.44
ALOX15 P16050 3/20 0.41
ALOX12 P18054 2/20 0.41
CYP3A4 P08684 2/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
GPR35 Q9HC97 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
CHEK1 O14757 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12011755 1.00 PTPN1 (0.44) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL17880000 1.00 PTPN1 (0.44) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL14749884 0.93 PTPN1 (0.46) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL14186008 0.93 PTPN1 (0.50) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL677550 0.89 PTPN1 (0.44) PTPN1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL677492 0.89 PTPN1 (0.44) PTPN1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL17879953 0.88 ESR1 (0.42) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL30436898 0.88 ESR1 (0.42) PTPN1ALOX15ALOX12CYP3A4HPGD
SCHEMBL676768 0.85 PTPN1 (0.41) PTPN1ESR1ESR2CA1CA2
SCHEMBL677484 0.85 PTPN1 (0.41) PTPN1ESR1ESR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807716-B2 Oligomer (2,6-dimethylphenylene ether) together with fabrication method and cured product thereof CPC CORPORATION, TAIWAN (TW) 2023-11-07 US disclosed
US-20170088669-A1 PHOSPHORUS-CONTAINING POLYPHENYLENE OXIDE RESIN, ITS PREPARATION METHOD, METHOD FOR PREPARING PREPOLYMER OF PHOSPHORUS-CONTAINING POLYPHENYLENE OXIDE, RESIN COMPOSITION AND ITS APPLICATION Elite Material Co., Ltd. (TW) 2017-03-30 US disclosed
US-20170029619-A1 THERMOSETTING RESIN COMPOSITION, AND RESIN VARNISH, METAL FOIL WITH RESIN, RESIN FILM, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD USING THE SAME PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2017-02-02 US disclosed
US-9528026-B2 Resin composition, resin varnish, prepreg, metal-clad laminate, and printed wiring board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2016-12-27 US disclosed
US-9422394-B2 Thermoplastic polyurethane and associated method and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-08-23 US disclosed
US-20160168378-A1 POLY(PHENYLENE ETHER) RESIN COMPOSITION, PREPREG, METAL-CLAD LAMINATE, AND PRINTED-WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2016-06-16 US disclosed
US-20160145370-A1 POLYPHENYLENE ETHER RESIN COMPOSITION, PREPREG, METAL-CLAD LAMINATE AND PRINTED WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2016-05-26 US disclosed
US-20160090457-A1 PREPREG, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2016-03-31 US disclosed
US-9296916-B2 Poly(phenylene ether)/epoxy homogeneous solid and powder coating composition incorporating same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-29 US disclosed
US-9266997-B2 Polyurethane foam and associated method and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-02-23 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-8053077-B2 Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-08 US disclosed
US-20110152431-A1 FLAME RETARDANT POLYAMIDE COMPOSITION, METHOD, AND ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110152471-A1 METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER, MULTIBLOCK COPOLYMERS PRODUCED THEREBY, AND ASSOCIATED COMPOSITIONS AND ARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110152420-A1 POLY(ARYLENE ETHER)/POLYAMIDE COMPOSITIONS, METHODS, AND ARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110046285-A1 POLYMER COMPOSITE MATERIAL, OPTICAL MATERIAL INCLUDING THE SAME, AND THERMOPLASTIC AROMATIC POLYMER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2011-02-24 US disclosed
US-7655278-B2 Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US disclosed
US-20080246173-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
US-20080071035-A1 CURABLE POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-20 US disclosed
US-20080071036-A1 CURED POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-20 US disclosed