SCHEMBL67751

SCHEMBL67751

CC1CC(=O)c2cc(Cl)ccc2S1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
KLK7 P49862 1/20 0.54
NPC1 O15118 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
VHL P40337 1/20 0.50
ELOC Q15369 1/20 0.50
ELOB Q15370 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
BRD4 O60885 1/20 0.37
CREBBP Q92793 1/20 0.37
S100A4 P26447 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
MAPK13 O15264 1/20 0.37
DAPK3 O43293 1/20 0.37
ROCK2 O75116 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355203 1.00 KDM4E (0.54) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL4096555 0.87 KDM4E (0.63) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL13043709 0.84 VHL (0.55) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL13497572 0.81 VHL (0.53) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL12240274 0.81 KDM4E (0.55) KDM4EALDH1A1HPGDKLK7HTT
SCHEMBL10383073 0.81 KDM4E (0.55) KDM4EALDH1A1HPGDKLK7HTT
SCHEMBL9819297 0.80 KDM4E (0.54) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL8110022 0.80 KDM4E (0.54) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL10077371 0.80 KDM4E (0.54) KDM4EALDH1A1HPGDKLK7NPC1
SCHEMBL13070290 0.80 KDM4E (0.51) KDM4EALDH1A1HPGDKLK7NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57045185-A None JP disclosed
CN-119403840-A Photocurable composition, method for producing cured film, solid-state imaging element, image display device, and radical polymerization initiator 富士胶片株式会社 2025-02-07 CN disclosed
WO-2024181097-A1 PHOTOCURABLE COMPOSITION, METHOD FOR PRODUCING CURED ARTICLE, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2024-09-06 WO disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
EP-3689981-B1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM CORP (JP) 2024-07-10 EP disclosed
WO-2024043108-A1 PHOTOCURABLE COMPOSITION, METHOD FOR PRODUCING CURED FILM, FILM, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2024-02-29 WO disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-2853367-B1 Molding process, molded printed material, process for producing in-mold molded article, in-mold molded article, and decorative sheet FUJIFILM CORP (JP) 2022-12-07 EP disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed
US-20060167025-A1 Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs SCHERING AG (DE) 2006-07-27 US disclosed
WO-2006066950-A2 TRICYCLIC AMINOALCOHOLS, METHODS FOR PRODUCING THE SAME AND THEIR USE AS ANTI-INFLAMMATORY AGENTS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-06-29 WO disclosed
US-4874869-A TREATMENT OF DIABETIC COMPLICATIONS, CATARACTS EISAI CO., LTD. (JP) 1989-10-17 US disclosed
US-4780472-A Hydantoin derivatives for treating complications of diabetes EISAI CO., LTD. (JP) 1988-10-25 US disclosed
US-4540704-A Treating complications of diabetes mellitus with hydantoin derivatives EISAI CO., LTD. (JP) 1985-09-10 US disclosed
JP-S5745185-A HYDANTOIN DERIVATIVE AND ITS PREPARATION EISAI CO LTD 1982-03-13 JP disclosed
JP-S05745185-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167025-A1 Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs ALDH7A1, NOTUM, GOT2 KDM4E 3144/4885ALDH1A1 62/4885HPGD 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.