Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772546 | 0.91 | PDE5A (0.71) | PDE5APDE6C | |
| SCHEMBL6772837 | 0.86 | PDE5A (1.00) | PDE5APDE6C | |
| SCHEMBL6775838 | 0.86 | PDE5A (0.77) | PDE5APDE6C | |
| SCHEMBL6778727 | 0.85 | PDE5A (0.72) | PDE5APDE6C | |
| SCHEMBL6631130 | 0.84 | PDE5A (0.75) | PDE5APDE6C | |
| SCHEMBL6777498 | 0.83 | PDE5A (1.00) | PDE5APDE6C | |
| SCHEMBL6778729 | 0.82 | PDE5A (0.72) | PDE5APDE6C | |
| SCHEMBL6773582 | 0.82 | PDE5A (1.00) | PDE5APDE6C | |
| SCHEMBL6359521 | 0.81 | PDE5A (1.00) | PDE5APDE6C | |
| SCHEMBL6773115 | 0.81 | PDE5A (1.00) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756373-B1 | SUCH AS 5-(2-BUTOXY-5-IODO-3-PYRIDINYL)-3-ETHYL-2-(2-METHOXY-ETHYL)-2,6-DIHYDRO-7H -PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE; CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; ERECTILE DYSFUNCTION | PFIZER INC. | 2004-06-29 | — | — | US | claimed |
| US-6756373-B1 | SUCH AS 5-(2-BUTOXY-5-IODO-3-PYRIDINYL)-3-ETHYL-2-(2-METHOXY-ETHYL)-2,6-DIHYDRO-7H -PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE; CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; ERECTILE DYSFUNCTION | PFIZER INC. | 2004-06-29 | — | — | US | disclosed |