Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 6/20 | 0.39 |
| ▸ | NOS1 | P29475 | 6/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743248 | 0.90 | HTR6 (0.51) | HTR6HTR1DHTR1BHTR7NOS3 | |
| SCHEMBL6745791 | 0.90 | HTR6 (0.51) | HTR6HTR1DHTR1BHTR7NOS3 | |
| SCHEMBL6740739 | 0.86 | HTR1B (0.51) | HTR6HTR1DHTR1BHTR7 | |
| SCHEMBL6744614 | 0.82 | HTR6 (0.47) | HTR6HTR1DHTR1BHTR7NOS3 | |
| SCHEMBL6744609 | 0.82 | HTR6 (0.47) | HTR6HTR1DHTR1BHTR7NOS3 | |
| SCHEMBL6742324 | 0.72 | HTR6 (0.45) | HTR6HTR1DHTR1BNOS3NOS1 | |
| SCHEMBL6948541 | 0.71 | HTR6 (0.44) | HTR6HTR1DHTR1BNOS3NOS1 | |
| SCHEMBL6948549 | 0.71 | HTR6 (0.44) | HTR6HTR1DHTR1BNOS3NOS1 | |
| SCHEMBL6745125 | 0.70 | HTR6 (0.43) | HTR6HTR1DHTR1BNOS3NOS1 | |
| SCHEMBL28319002 | 0.69 | HTR1B (0.46) | HTR6HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716837-B1 | INDOLE AND INDAZOLE COMPOUNDS | NPS ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 2004-04-06 | — | — | US | disclosed |