Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6771855 | 0.77 | F10 (0.39) | F10PTPN1 | |
| Trifluoroacetic Acid SCHEMBL6769296 | 0.74 | F10 (0.40) | F10PTPN1 | |
| SCHEMBL6553856 | 0.73 | HDAC3 (0.47) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3911676 | 0.73 | AAK1 (0.44) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3909952 | 0.73 | AAK1 (0.44) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22526181 | 0.72 | ITGB3 (0.44) | HDAC8ATM | |
| SCHEMBL30169343 | 0.71 | ATM (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22527004 | 0.70 | ATM (0.42) | F10AAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL30169063 | 0.70 | ATM (0.42) | F10AAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL22526731 | 0.70 | ATM (0.40) | F10AAK1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |