Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782472 | 0.91 | FAAH (0.47) | MAPTFAAHKMT2AALDH1A1TLR7 | |
| SCHEMBL6772971 | 0.89 | CCR3 (0.39) | NPC1RAB9ATP53MAPTFAAH | |
| SCHEMBL6782943 | 0.88 | CCR3 (0.43) | NPC1RAB9AMAPTCCR3HTR2A | |
| SCHEMBL6782550 | 0.85 | TLR7 (0.40) | NPC1RAB9ATP53MAPTFAAH | |
| SCHEMBL6894553 | 0.85 | HDAC3 (0.44) | NPC1RAB9ATP53MAPTFAAH | |
| SCHEMBL6781852 | 0.85 | CCR3 (0.42) | NPC1RAB9ATP53MAPTCCR3 | |
| SCHEMBL6779395 | 0.84 | TLR7 (0.46) | NPC1RAB9ATP53MAPTKMT2A | |
| SCHEMBL6773388 | 0.84 | TLR7 (0.37) | TP53MAPTKMT2AALDH1A1GAA | |
| SCHEMBL6096076 | 0.84 | TLR7 (0.45) | RAB9AGAASMN1; SMN2TLR7 | |
| SCHEMBL6771963 | 0.82 | MAPT (0.46) | NPC1RAB9ATP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |