Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990839 | 0.83 | ATM (0.57) | HTR1BATMGPR35KMT2AMEN1 | |
| SCHEMBL4996207 | 0.83 | ATM (0.45) | HTR1BATMGPR35KMT2AMEN1 | |
| SCHEMBL4988326 | 0.82 | HTR1B (0.57) | HTR1BATMGPR35KMT2AMEN1 | |
| SCHEMBL4985772 | 0.82 | GPR35 (0.50) | HTR1BATMGPR35CDK2 | |
| Hydrochloric Acid SCHEMBL4985151 | 0.82 | ATM (0.56) | HTR1BATMGPR35KMT2AMEN1 | |
| SCHEMBL4982825 | 0.82 | GPR35 (0.47) | HTR1BATMGPR35KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4985854 | 0.81 | GPR35 (0.49) | HTR1BATMGPR35CDK2 | |
| Hydrochloric Acid SCHEMBL4988384 | 0.81 | HTR1B (0.56) | HTR1BATMGPR35KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4990477 | 0.81 | GPR35 (0.46) | HTR1BATMGPR35KMT2AMEN1 | |
| SCHEMBL4985501 | 0.80 | GPR35 (0.52) | HTR1BATMGPR35KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812225-B2 | PYSCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | ASTRAZENECA AB (SE) | 2004-11-02 | — | — | US | disclosed |