Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777954 | 0.90 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6782828 | 0.89 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL6776799 | 0.87 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6285998 | 0.85 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6779814 | 0.85 | FAAH (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL6774169 | 0.84 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL6782676 | 0.84 | EPHX1 (0.41) | — | |
| SCHEMBL6776787 | 0.83 | MEN1 (0.42) | TLR7TLR8 | |
| SCHEMBL6775141 | 0.83 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6778782 | 0.82 | TLR7 (0.44) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |