Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576134 | 0.80 | AKR1C1 (0.41) | AKR1C1SMN1; SMN2HDAC4MEN1KMT2A | |
| SCHEMBL6021972 | 0.80 | AKR1C1 (0.41) | AKR1C1SMN1; SMN2HDAC4MEN1KMT2A | |
| SCHEMBL28564028 | 0.76 | DRD3 (0.38) | DPP4DRD3MEN1KMT2A | |
| SCHEMBL7518558 | 0.76 | GAA (0.34) | AKR1C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4735252 | 0.74 | DRD3 (0.46) | AKR1C1HDAC4DPP4DRD3 | |
| SCHEMBL7894906 | 0.74 | AKR1C1 (0.39) | AKR1C1SMN1; SMN2HDAC4MEN1POLB | |
| SCHEMBL2861574 | 0.73 | DRD3 (0.45) | AKR1C1HDAC4DRD3MEN1KMT2A | |
| SCHEMBL27745169 | 0.73 | DRD3 (0.45) | AKR1C1HDAC4DRD3MEN1KMT2A | |
| SCHEMBL5641960 | 0.71 | DRD3 (0.43) | AKR1C1HDAC4DPP4DRD3MEN1 | |
| SCHEMBL7518367 | 0.70 | KMT2A (0.40) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770780-B1 | QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS | JSR CORPORATION (JP) | 2004-08-03 | — | — | US | disclosed |
| EP-1231205-A1 | VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS | JSR Corporation (JP) | 2002-08-14 | — | — | EP | disclosed |