Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24437339 | 0.88 | MEN1 (0.38) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL888267 | 0.80 | HDAC3 (0.47) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4399856 | 0.80 | HDAC3 (0.40) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3418695 | 0.77 | GSK3B (0.42) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL14441948 | 0.77 | HDAC3 (0.44) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21316476 | 0.74 | NAMPT (0.46) | BRD4NPC1RAB9AMEN1GAA | |
| SCHEMBL1986577 | 0.73 | GSK3B (0.43) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL12604847 | 0.73 | HDAC3 (0.54) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3415059 | 0.73 | GSK3B (0.39) | GSK3BDYRK1A | |
| SCHEMBL7079271 | 0.73 | RPS6KA3 (0.43) | KMT2AGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524899-B2 | Oligopeptide containing fused 6-membered ring forming complexes with double stranded dna; complexes can be used for identification of specific dsDNA sequences, inhibiting gene transcription, therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific gene | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524899-B2 | Oligopeptide containing fused 6-membered ring forming complexes with double stranded dna; complexes can be used for identification of specific dsDNA sequences, inhibiting gene transcription, therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific gene | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-09-03 | — | — | US | disclosed |
| US-6683189-B1 | POLYAMIDE-OLIGONUCLEOTIDE CONJUGATES; NETROPSIN AND DISTAMYCIN A SYNTHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-01-27 | — | — | US | disclosed |
| US-6545162-B1 | Solid phase biosynthesis of viricide antibiotic | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-04-08 | — | — | US | disclosed |
| EP-0885189-B9 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0885189-B1 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6090947-A | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-18 | — | — | US | disclosed |