Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777572 | 0.88 | SIRT2 (0.46) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL24437376 | 0.81 | HPSE (0.38) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL3418695 | 0.74 | GSK3B (0.42) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL23260703 | 0.74 | SMN1; SMN2 (0.47) | NPC1GAARAB9AKMT2AHPSE | |
| SCHEMBL6428501 | 0.71 | GSK3B (0.41) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL21316476 | 0.71 | NAMPT (0.46) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL1986577 | 0.71 | GSK3B (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL7079271 | 0.70 | RPS6KA3 (0.43) | KMT2A | |
| SCHEMBL3415059 | 0.70 | GSK3B (0.39) | — | |
| SCHEMBL25734944 | 0.70 | HPSE (0.50) | MEN1NPC1RAB9AKMT2AHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153727-A1 | METHOD FOR PRODUCING PYRROLE-IMIDAZOLE (POLY)AMIDE | KANEKA CORPORATION (JP) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153727-A1 | METHOD FOR PRODUCING PYRROLE-IMIDAZOLE (POLY)AMIDE | DDC, PAM, AADAC | MEN1 3539/4885NPC1 4631/4885GAA 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.