Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779480 | 0.96 | TDP1 (0.62) | TDP1CRHR1 | |
| SCHEMBL6780429 | 0.83 | CRHR1 (0.54) | TDP1CRHR1 | |
| SCHEMBL9276132 | 0.81 | CRHR1 (0.56) | TDP1CRHR1 | |
| SCHEMBL6779165 | 0.81 | CRHR1 (0.51) | TDP1CRHR1 | |
| SCHEMBL6774578 | 0.80 | CRHR1 (0.56) | TDP1CRHR1 | |
| SCHEMBL6778808 | 0.80 | CRHR1 (0.48) | TDP1CRHR1 | |
| SCHEMBL6780425 | 0.79 | CRHR1 (0.53) | TDP1CRHR1 | |
| SCHEMBL9390744 | 0.78 | CRHR1 (0.51) | TDP1CRHR1 | |
| SCHEMBL9393697 | 0.76 | CRHR1 (0.52) | TDP1CRHR1 | |
| SCHEMBL9390738 | 0.75 | CRHR1 (0.53) | TDP1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765008-B1 | PYRROLO(2,3-D)PYRIMIDINE DERIVATIVES; ANXIOLYTIC AGENTS; NERVOUS SYSTEM, BRAIN, PSYCHOLOGICAL, EATING, AND GASTROINTESTINAL DISORDERS; CORTICOTROPIN-RELEASING FACTOR ANTAGONISTS | PFIZER INC | 2004-07-20 | — | — | US | disclosed |