Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6378948 | 0.81 | TPMT (0.39) | SLC1A3SLC1A2SLC1A1RXRARXRB | |
| SCHEMBL7356667 | 0.81 | SLC1A1 (0.39) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6378952 | 0.81 | TPMT (0.39) | SLC1A3SLC1A2SLC1A1RXRARXRB | |
| Hydrochloric Acid SCHEMBL6779507 | 0.79 | TPMT (0.38) | RXRARXRB | |
| SCHEMBL6773156 | 0.79 | KMT2A (0.40) | RXRARXRB | |
| SCHEMBL6780474 | 0.78 | TTR (0.43) | CRHBPCRHR2 | |
| SCHEMBL6779107 | 0.78 | TTR (0.43) | — | |
| SCHEMBL2298439 | 0.78 | DPP4 (0.48) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7426518 | 0.78 | DPP4 (0.48) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6783703 | 0.77 | TTR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831199-B1 | In order to avoid bleeding side-effects when treating the conditions associated with integrin alpha v beta 3, it is beneficial to have compounds which are selective antagonists for alpha v beta 3 versus alpha IIb beta 3 | G. D. SEARLE & CO. | 2004-12-14 | — | — | US | disclosed |