Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.44 |
| ▸ | GABRP | O00591 | 5/20 | 0.44 |
| ▸ | GABRD | O14764 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.44 |
| ▸ | GABRE | P78334 | 5/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473643 | 0.85 | KDM4E (0.41) | CYP1A2GABRA2GABRB2GABRPGABRD | |
| SCHEMBL18893829 | 0.80 | CYP1A2 (0.45) | CYP1A2GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6783355 | 0.77 | CYP1A2 (0.35) | CYP1A2MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL23496544 | 0.77 | NPC1 (0.48) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL23354891 | 0.76 | ALDH1A1 (0.52) | CYP1A2GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL1562633 | 0.76 | TP53 (0.45) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL17610703 | 0.74 | ALDH1A1 (0.56) | CYP1A2GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL20746109 | 0.74 | GAA (0.46) | CYP1A2GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10817937 | 0.73 | ALDH1A1 (0.59) | CYP1A2GABRA2GABRB2GABRPGABRD | |
| SCHEMBL3144115 | 0.73 | HPGD (0.44) | GABRA2GABRB2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809101-B2 | RNA POLYMERASES INHIBITORS; SUCH AS 5-(1-HYDROXY-1-(5-METHYL-OXAZOL-2-YL))METHYLENE-2-THIOXOTHIAZOLIDIN-4-ONE | SHIONOGI & CO., LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| US-20030203948-A1 | Compounds having anti-hepatitics c virus effect | Z-KAT, INC. | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203948-A1 | Compounds having anti-hepatitics c virus effect | NSUN3, HCCS, NSUN2 | CYP1A2 816/4885GABRA2 4501/4885GABRB2 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.