Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 1.00 |
| ▸ | CCR2 | P41597 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.90 |
| ▸ | ATM | Q13315 | 1/20 | 0.90 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781571 | 0.95 | RXFP1 (1.00) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL14563954 | 0.88 | RXFP1 (0.87) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6776725 | 0.87 | RXFP1 (1.00) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6781611 | 0.87 | CCR1 (1.00) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6782671 | 0.86 | CCR1 (1.00) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL13662472 | 0.82 | MAPT (0.84) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6781447 | 0.80 | CCR1 (0.74) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6779535 | 0.80 | MEN1 (0.80) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL6483258 | 0.77 | KDM4E (1.00) | CCR1CCR2RXFP1ATMMEN1 | |
| SCHEMBL15709491 | 0.77 | CCR1 (0.82) | CCR1CCR2RXFP1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |