Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783729 | 0.94 | TLR7 (0.37) | TLR7CYP3A4RELAKDM4EALDH1A1 | |
| SCHEMBL6777327 | 0.89 | TLR7 (0.34) | TLR7PIM1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6778418 | 0.84 | TLR7 (0.39) | TLR7PIM1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4794387 | 0.84 | CSNK2A1 (0.35) | TLR7CYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL5031355 | 0.84 | TLR7 (0.40) | TLR7PIM1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5338446 | 0.83 | CSNK2A1 (0.34) | TLR7CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL4793436 | 0.82 | KDM4E (0.35) | TLR7CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL4872231 | 0.82 | CSNK2A1 (0.35) | TLR7PIM1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6783236 | 0.81 | GRIA1 (0.33) | TLR7 | |
| SCHEMBL4870279 | 0.81 | TLR7 (0.48) | TLR7RELATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |