SCHEMBL6783236

SCHEMBL6783236

Cc1nc(N)c2nc(C)n(CCNS(=O)(=O)C(C)C)c2c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 3/20 0.33
TLR7 Q9NYK1 3/20 0.30
NPY5R Q15761 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6773932 0.93 GRIA1 (0.38) GRIA1TLR7NPY5RCA12CA1
SCHEMBL5031355 0.86 TLR7 (0.40) TLR7CA12CA1CA2CA9
SCHEMBL6777327 0.86 TLR7 (0.34) TLR7CA12CA1CA2CA9
SCHEMBL6779020 0.81 TLR7 (0.33) TLR7
SCHEMBL6773797 0.79 KMT2A (0.43) TLR7
SCHEMBL6287590 0.79 TLR7 (0.46) TLR7CA12CA1CA2CA9
SCHEMBL6778418 0.79 TLR7 (0.39) TLR7CA12CA1CA2CA9
SCHEMBL6780037 0.78 CYP3A4 (0.40) TLR7CA12CA1CA2CA9
SCHEMBL6095597 0.78 TLR7 (0.50) TLR7NPY5R
SCHEMBL6096758 0.78 MEN1 (0.42) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696465-B2 INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES 3M INNOVATIVE PROPERTIES COMPANY 2004-02-24 US claimed