Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | PYGL | P06737 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834652 | 0.86 | KMT2A (0.70) | KMT2AMEN1LMNAPYGLSMN1; SMN2 | |
| SCHEMBL24233277 | 0.85 | SMN1; SMN2 (0.70) | KMT2AMEN1PYGLHTTSMN1; SMN2 | |
| SCHEMBL31103641 | 0.83 | MEN1 (0.76) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 | |
| SCHEMBL1572442 | 0.83 | MEN1 (0.76) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 | |
| SCHEMBL30205486 | 0.83 | ALOX5 (0.69) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL28012109 | 0.82 | KMT2A (0.68) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| Fluoride SCHEMBL28307367 | 0.82 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 | |
| Methane SCHEMBL28043489 | 0.82 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 | |
| Ammonia Solution, Strong SCHEMBL27704150 | 0.82 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 | |
| SCHEMBL27858189 | 0.82 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2IRAK4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20020156281-A1 | Amide inhibitors of microsomal triglyceride transfer protein | BOOTH RICHARD JOHN (US) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156281-A1 | Amide inhibitors of microsomal triglyceride transfer protein | CETP, MTTP, LCAT | KMT2A 1440/4885MEN1 4612/4885LMNA 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.