Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KRAS | P01116 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779204 | 1.00 | TNFRSF1A (0.77) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5697761 | 0.89 | TNFRSF1A (0.81) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5697764 | 0.89 | TNFRSF1A (0.81) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30674925 | 0.87 | TNFRSF1A (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3215700 | 0.87 | TNFRSF1A (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30383266 | 0.87 | TNFRSF1A (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3215707 | 0.87 | TNFRSF1A (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28261935 | 0.86 | TNFRSF1A (0.82) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7188106 | 0.84 | MAPT (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7188111 | 0.84 | MAPT (1.00) | TNFRSF1AMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
| US-6677383-B1 | SUPRRESION OF TUMORS CONTAINING OXIDOREDUCTASE ENZYMES, BY CONTACTING THE CELLS WITH ANTITUMOR CHEMICAL INTERMEDIATES SUCH AS 3,4,5-TRIMETHOXY-4'-METHOXYSTILBENE | DE MONTFORT UNIVERSITY (GB) | 2004-01-13 | — | — | US | disclosed |
| EP-1051383-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999040056-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | TNFRSF1A 4050/4885MAPT 4124/4885ALDH1A1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.