Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773388 | 0.91 | TLR7 (0.37) | TLR7TLR8KDM4EHSD17B10LMNA | |
| SCHEMBL6096076 | 0.89 | TLR7 (0.45) | TLR7TLR8SMN1; SMN2GAA | |
| SCHEMBL6772264 | 0.88 | TLR7 (0.45) | TLR7TLR8SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6096657 | 0.86 | LMNA (0.39) | TLR7TLR8SMN1; SMN2LMNARECQL | |
| SCHEMBL6772921 | 0.86 | TLR7 (0.44) | TLR7TLR8KMT2AALDH1A1 | |
| SCHEMBL6773630 | 0.85 | TLR8 (0.36) | TLR7TLR8SMN1; SMN2HTTHPGD | |
| SCHEMBL6773525 | 0.84 | TLR7 (0.41) | TLR7TLR8 | |
| SCHEMBL6773179 | 0.84 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL6778890 | 0.84 | TLR7 (0.40) | TLR7TLR8KDM4EHSD17B10HPGD | |
| SCHEMBL6779395 | 0.84 | TLR7 (0.46) | TLR7TLR8SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |