Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779502 | 0.91 | MEN1 (0.82) | MEN1KMT2AKDM4ETDP1HTT | |
| SCHEMBL6776780 | 0.89 | RXFP1 (0.66) | MEN1KMT2AKDM4ETDP1ALOX12 | |
| SCHEMBL6781053 | 0.88 | MEN1 (0.79) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6785309 | 0.88 | MEN1 (0.79) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6779603 | 0.87 | KDM4E (0.64) | MEN1KMT2AKDM4ETDP1ALOX12 | |
| SCHEMBL6781607 | 0.87 | MEN1 (1.00) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL6781375 | 0.86 | KDM4E (0.60) | MEN1KMT2AKDM4ETDP1ALOX12 | |
| SCHEMBL6785134 | 0.86 | MEN1 (0.65) | MEN1KMT2AKDM4ETDP1ALOX12 | |
| SCHEMBL6782138 | 0.85 | KDM4E (0.59) | MEN1KMT2AKDM4ETDP1ALOX12 | |
| SCHEMBL6777321 | 0.84 | TDP1 (0.62) | MEN1KMT2AKDM4ETDP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |