Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781400 | 0.89 | MEN1 (0.72) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6779603 | 0.82 | KDM4E (0.64) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL16904825 | 0.80 | ALOX15 (0.63) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3706362 | 0.79 | USP7 (0.67) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL29619258 | 0.79 | USP7 (0.67) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL6781375 | 0.79 | KDM4E (0.60) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL6776780 | 0.78 | RXFP1 (0.66) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL15563413 | 0.78 | ALOX15 (0.60) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16244781 | 0.77 | TDP1 (0.68) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL6785134 | 0.76 | MEN1 (0.65) | TDP1ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |