Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783346 | 0.91 | TLR7 (0.38) | MEN1KMT2ATGFBR1LMNAALDH1A1 | |
| SCHEMBL6780086 | 0.89 | TLR7 (0.41) | MEN1KMT2ATSHRTGFBR1SMN1; SMN2 | |
| SCHEMBL6780432 | 0.87 | KMT2A (0.43) | MEN1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6780316 | 0.86 | TLR7 (0.38) | TSHRTGFBR1LMNATLR7TLR8 | |
| SCHEMBL6282958 | 0.86 | TLR7 (0.36) | MEN1KMT2AKDM4ETGFBR1LMNA | |
| SCHEMBL6282956 | 0.86 | TLR7 (0.36) | MEN1KMT2AKDM4ETGFBR1LMNA | |
| SCHEMBL6779023 | 0.85 | GAA (0.40) | GAATLR7TLR8 | |
| SCHEMBL6281876 | 0.85 | TLR7 (0.38) | LMNATLR7TLR8 | |
| SCHEMBL6780878 | 0.82 | TLR7 (0.36) | TGFBR1TLR7TLR8 | |
| SCHEMBL6284763 | 0.82 | ALDH1A1 (0.39) | GAAALDH1A1TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |