Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843199 | 0.87 | HRAS (0.47) | HRASESR1ESR2HDAC1HDAC2 | |
| SCHEMBL5889539 | 0.85 | HRAS (0.60) | HRASESR1ESR2HDAC1HDAC2 | |
| SCHEMBL5889621 | 0.84 | HRAS (0.54) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5889846 | 0.83 | HRAS (0.54) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL1842501 | 0.82 | HDAC1 (0.48) | HRASESR1ESR2HDAC1HDAC2 | |
| SCHEMBL3563935 | 0.82 | HRAS (0.43) | HRASESR1ESR2HDAC1HDAC2 | |
| SCHEMBL1843141 | 0.81 | SIGMAR1 (0.47) | HDAC1HDAC2HDAC8PRKCAKDM4E | |
| SCHEMBL5677699 | 0.80 | HRAS (0.50) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL1842079 | 0.80 | HRAS (0.55) | HRASESR1ESR2HDAC1HDAC2 | |
| SCHEMBL5896881 | 0.79 | HRAS (0.51) | HRASESR1ESR2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467969-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | The University of Strathclyde (GB) | 2004-10-20 | — | — | EP | claimed |
| WO-2003059881-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2003-07-24 | — | — | WO | claimed |