Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784702 | 0.83 | CYP2C9 (0.46) | KMT2AHTTTSHRMEN1ALDH1A1 | |
| SCHEMBL6773797 | 0.80 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL6780037 | 0.79 | CYP3A4 (0.40) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6778303 | 0.79 | MEN1 (0.40) | KMT2AHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL6777327 | 0.78 | TLR7 (0.34) | — | |
| SCHEMBL5031355 | 0.78 | TLR7 (0.40) | HTT | |
| SCHEMBL6780566 | 0.78 | CYP3A4 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL6778933 | 0.77 | LMNA (0.40) | SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL6780266 | 0.77 | CYP2C9 (0.44) | KMT2AHTTTSHRMEN1ALDH1A1 | |
| SCHEMBL6778251 | 0.77 | MEN1 (0.43) | KMT2AHTTTSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |