SCHEMBL67802

SCHEMBL67802

Cc1cc(Cl)cc(Cc2cc(Cl)cc(C)c2O)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 5/20 0.53
CYP2C19 P33261 5/20 0.53
HIF1A Q16665 4/20 0.53
HSD17B10 Q99714 4/20 0.52
HPGD P15428 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HSP90AA1 P07900 2/20 0.48
SHBG P04278 1/20 0.45
CYP3A4 P08684 4/20 0.45
HSPA5 P11021 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 2/20 0.45
ALOX15 P16050 2/20 0.45
MEN1 O00255 1/20 0.45
SLC22A1 O15245 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
HSPD1 P10809 1/20 0.45
IDO1 P14902 1/20 0.45
ALOX12 P18054 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898482 0.88 CYP2C9 (0.52) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL12786466 0.88 CYP2C9 (0.52) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL10982291 0.85 MAPT (0.50) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL13888157 0.84 CYP2C9 (0.43) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL8822919 0.83 CYP3A4 (0.57) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL23201145 0.83 CYP2C9 (0.39) CYP2C9CYP2C19HIF1AHSD17B10HPGD
Hydrochloric Acid SCHEMBL30387703 0.81 CYP2C9 (0.38) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL1182540 0.80 CA1 (0.58) CYP2C9HSD17B10HPGDALDH1A1CYP3A4
SCHEMBL10826237 0.79 LDHA (0.47) CYP2C9CYP2C19HIF1AHSD17B10HPGD
SCHEMBL19419899 0.77 CYP2C9 (0.59) CYP2C9CYP2C19HIF1AHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9545624-B2 Nickel containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2017-01-17 US disclosed
US-9545624-B2 Nickel containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2017-01-17 US disclosed
US-9371422-B2 Titanium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-06-21 US disclosed
US-9371422-B2 Titanium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-06-21 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9221041-B2 Iridium containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-12-29 US disclosed
US-9221041-B2 Iridium containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-12-29 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
WO-2013052585-A2 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-04-11 WO disclosed
WO-2013043767-A2 RHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed
WO-2013043792-A2 COPPER CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed
WO-2013043785-A2 NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4234742-A ANTICHOLESTEROL AGENTS HEXACHIMIE (FR) 1980-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP2C9 2591/4885CYP2C19 3009/4885HIF1A 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.