Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483981 | 0.84 | — | — | |
| SCHEMBL6444738 | 0.82 | KDM4E (0.35) | ALDH1A1RECQLTDP1L3MBTL1 | |
| SCHEMBL1735246 | 0.81 | — | — | |
| SCHEMBL1736012 | 0.79 | CAMK2A (0.32) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL4217404 | 0.78 | CAMK2A (0.31) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14398795 | 0.78 | MEN1 (0.35) | ALDH1A1HPGDTSHRL3MBTL1PDE4A | |
| SCHEMBL30979835 | 0.77 | NPC1 (0.34) | — | |
| SCHEMBL11107864 | 0.76 | — | — | |
| SCHEMBL7361344 | 0.76 | — | — | |
| SCHEMBL5163595 | 0.75 | L3MBTL1 (0.35) | HPGDTSHRRECQLSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713632-B1 | Process for the preparation of imidazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1193258-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |