Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966982 | 0.84 | AKR1C3 (0.63) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL122093 | 0.84 | AKR1C3 (0.63) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL51774 | 0.84 | AKR1C3 (0.63) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL6790383 | 0.83 | DHODH (0.50) | DHODH | |
| SCHEMBL31623020 | 0.83 | DHODH (0.49) | DHODHKDM4EALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL4084710 | 0.83 | DHODH (0.49) | DHODHKDM4EALDH1A1L3MBTL1AKR1C3 | |
| Hydrochloric Acid SCHEMBL27571578 | 0.83 | AKR1C3 (0.61) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL4084715 | 0.83 | DHODH (0.49) | DHODHKDM4EALDH1A1L3MBTL1AKR1C3 | |
| Hydrochloric Acid SCHEMBL6780341 | 0.83 | AKR1C3 (0.61) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL10362729 | 0.80 | DHODH (0.56) | DHODHKDM4EALDH1A1L3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727250-B2 | ADMINISTERING COMPOUNDS SUCH AS TRANS-3-(NAPHTH-2-YL)-BUT-2-ENOIC ACID-N-(2-CARBOXY-PHENYL)-AMIDE OR LIKE FOR THERAPY OF CONDITIONS ASSOCIATED WITH INCREASED TELOMERASE ACTIVITY, E.G. TUMOUR DISEASES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-04-27 | — | — | US | disclosed |
| CN-1414849-A | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation | BOEHRINGER INGECHEIM PHARMA KG (DE) | 2003-04-30 | — | — | CN | disclosed |
| US-20020099089-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-07-25 | — | — | US | disclosed |
| US-6362210-B1 | ANTITUMOR, ANTICANCER AGENT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099089-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation | TERT, NAT1, POT1 | DHODH 1011/4885KDM4E 1243/4885ALDH1A1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.