SCHEMBL6780794

SCHEMBL6780794

CC(I)O[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704968 0.72
SCHEMBL5476453 0.69
SCHEMBL27637204 0.69
SCHEMBL4017650 0.67 ALDH1A1 (0.31)
SCHEMBL2655903 0.67
SCHEMBL25402418 0.67
SCHEMBL22492693 0.67
SCHEMBL30139059 0.65
SCHEMBL2684896 0.61
SCHEMBL15142389 0.61 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029897-A1 Frangible compounds for pathogen inactivation CERUS CORPORATION (US) 2004-02-12 US disclosed
EP-1364944-A1 Frangible Compounds for Pathogen Inactivation Cerus Corporation (US) 2003-11-26 EP disclosed
EP-1021414-B1 FRANGIBLE COMPOUNDS FOR PATHOGEN INACTIVATION CERUS CORP (US) 2003-06-18 EP disclosed
US-6514987-B1 Useful for inactivating pathogens in a material, such as a blood product, and then degrades to breakdown products CERUS CORPORATION 2003-02-04 US disclosed
EP-1021414-A1 FRANGIBLE COMPOUNDS FOR PATHOGEN INACTIVATION Cerus Corporation (US) 2000-07-26 EP disclosed
US-6093725-A A BINDER FOR DEACTIVATING PATHOGENS IN A BLOOD SAMPLE TO BIND NUCLEIC ACID BY COVALENT LINKAGE CERUS CORPORATION (US) 2000-07-25 US disclosed
EP-1005531-A2 METHOD OF TREATING LEUKOCYTES, LEUKOCYTE COMPOSITIONS AND METHODS OF USE THEREOF Cerus Corporation (US) 2000-06-07 EP disclosed
CN-1248245-A Friable compounds for pathogen inactivation CERUS CORP (US) 2000-03-22 CN disclosed
WO-1999003976-A2 METHOD OF TREATING LEUKOCYTES, LEUKOCYTE COMPOSITIONS AND METHODS OF USE THEREOF CERUS CORPORATION (US) 1999-01-28 WO disclosed
WO-1998030545-A9 FRANGIBLE COMPOUNDS FOR PATHOGEN INACTIVATION 1998-12-30 WO disclosed
WO-1998030545-A1 FRANGIBLE COMPOUNDS FOR PATHOGEN INACTIVATION CERUS CORPORATION (US) 1998-07-16 WO disclosed